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Interpret Your Complement C3 Results
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Complement C3 Normal Ranges
C3 (Complement component 3) is the most abundant protein in the complement system — the arm of innate immunity responsible for clearing pathogens and immune complexes.
| Age Group | Reference Range | Unit | Notes |
|---|---|---|---|
| Adults (18–64) | 90 – 180 | mg/dL | — |
Also reported in: g/L.
Common Causes of High C3
Acute phase reaction (infection, trauma, malignancy — C3 is an acute phase protein)ObesityPregnancy
Common Causes of Low C3
Active SLE / lupus nephritis (immune complex consumption — most common clinical cause)Membranoproliferative glomerulonephritis (MPGN) with C3 nephritic factorPost-streptococcal glomerulonephritis (transient, normalizes within weeks)
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Reference ranges, causes, symptoms, preparation, and FAQs.