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immunology

Complement C4

C4· also: Complement C4

Clinical Overview

C4 is a complement protein involved in immune complex clearance. Low C4 with low C3 strongly suggests active lupus. C4 can also be low in hereditary angioedema.

Reference RangesWHO/IFCC standards

Age GroupReference RangeUnitNotes
Adults (18–64)16 – 47mg/dL

Also reported in: g/L.

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Related Topics

autoimmunelupusangioedema

Related Tests