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Interpret Your Rheumatoid Factor Results

Enter your RF value below and get an instant, free AI interpretation — a plain-English explanation checked against WHO/IFCC reference ranges.

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This AI-generated interpretation is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Results may vary based on individual health factors not captured here.

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Rheumatoid Factor Normal Ranges

Rheumatoid Factor (RF) is an autoantibody — typically IgM — directed against the Fc portion of IgG immunoglobulin.

Reference RangeUnitNotes
0 – 14IU/mLNegative <14

Common Causes of High RF

Rheumatoid Arthritis (RA) — most common clinical indicationSjögren's syndrome (often very high RF)SLE (systemic lupus erythematosus)

Common Causes of Low RF

Approximately 20–30% of RA patients are "seronegative" — RF negative — especially early in diseaseNegative RF does not exclude RA (seronegative RA exists)

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