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Interpret Your Immunoglobulin G Results
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Immunoglobulin G Normal Ranges
IgG is the most abundant immunoglobulin in blood, comprising approximately 75% of total immunoglobulins.
| Age Group | Reference Range | Unit | Notes |
|---|---|---|---|
| Adults (18–64) | 700 – 1600 | mg/dL | — |
| Children / Pediatric | 400 – 1200 | mg/dL | Age-dependent; rises through childhood |
Also reported in: g/L.
Common Causes of High IgG
Chronic infections (tuberculosis, HIV, hepatitis C, osteomyelitis)Autoimmune liver disease (autoimmune hepatitis, primary biliary cholangitis)IgG multiple myeloma (monoclonal — paraprotein spike on SPEP)
Common Causes of Low IgG
Common Variable Immunodeficiency (CVID) — most common primary immunodeficiency in adultsX-linked agammaglobulinemia (XLA) — severe congenital B cell deficiencySecondary immunodeficiency: CLL, lymphoma, post-rituximab therapy, high-dose steroids
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