Interpret Your Aspartate Aminotransferase Results
Enter your AST value below and get an instant, free AI interpretation — a plain-English explanation checked against WHO/IFCC reference ranges.
Medical Disclaimer
This AI-generated interpretation is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Results may vary based on individual health factors not captured here.
Always consult a qualified healthcare professional before making any health decisions. Read full disclaimer →
Aspartate Aminotransferase Normal Ranges
AST is an enzyme found in liver, heart muscle, skeletal muscle, kidneys, brain, and red blood cells.
| Age Group | Sex | Reference Range | Unit | Notes |
|---|---|---|---|---|
| Adults (18–64) | Male | 10 – 40 | U/L | — |
| Adults (18–64) | Female | 10 – 35 | U/L | — |
Also reported in: IU/L.
Why Doctors Order the Aspartate Aminotransferase Test
The AST/ALT ratio is a powerful diagnostic tool. An AST:ALT ratio >2:1 (especially >3:1) with elevated GGT strongly suggests alcoholic liver disease.
How to Enter Your AST Result
Aspartate Aminotransferase can be reported in U/L or IU/L. Choose the unit printed next to your result on the lab report so it is compared with the matching reference range.
Reference ranges for AST differ between men and women, so entering your sex gives a more accurate reading.
What a Low or High AST Can Be Associated With
Below the reference range
- Not clinically significant
- Vitamin B6 (pyridoxine) deficiency (cofactor for AST — may falsely lower AST)
Above the reference range
- Liver diseases (hepatitis, cirrhosis, NAFLD) — same as ALT
- Acute myocardial infarction (MI)
- Skeletal muscle injury or rhabdomyolysis
- Strenuous exercise
- Alcoholic liver disease (typically AST:ALT >2:1)
These are common associations, not a diagnosis. A single result is read alongside your symptoms, history and other tests — discuss it with your doctor.
What Can Change Your AST Result
Before you read too much into a result, consider whether any of these applied:
- Strenuous exercise (significantly raises AST from muscle)
- Intramuscular injections (raises AST)
- Hemolysis in sample (AST in red blood cells is released)
- Alcohol ingestion
Preparing for the test: Avoid heavy exercise 24–48 hours before testing. No fasting required but preferred.
Symptoms That Often Prompt AST Testing
- Similar to liver injury: jaundice, fatigue, nausea
- Chest pain and shortness of breath (if cardiac origin)
- Muscle pain and dark urine (if muscle origin)
Want the full clinical guide to Aspartate Aminotransferase?
Reference ranges, causes, symptoms, preparation, and FAQs.