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Interpret Your Alkaline Phosphatase Results
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Alkaline Phosphatase Normal Ranges
ALP is an enzyme found in the liver (bile ducts), bone, intestine, kidneys, and placenta.
| Age Group | Sex | Reference Range | Unit | Notes |
|---|---|---|---|---|
| Adults (18–64) | All | 44 – 147 | U/L | — |
| Children / Pediatric | All | 100 – 400 | U/L | Physiologically higher during growth spurts |
| All ages | Female | 100 – 500 | U/L | Third trimester of pregnancy (placental ALP) |
Also reported in: IU/L.
Common Causes of High ALP
Liver: cholestasis, primary biliary cholangitis, PSC, drug-induced cholestasis, liver metastasesBone: Paget's disease, bone fractures healing, bone metastases, hyperparathyroidism, ricketsPhysiological: pregnancy (placental ALP), growth in children and adolescents
Common Causes of Low ALP
HypothyroidismPernicious anemiaZinc deficiency
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